Glucosamine prevents in vitro collagen degradation in chondrocytes by inhibiting advanced lipoxidation reactions and protein oxidation.

Osteoarthritis affects a large segment of the aging population and is a major cause of pain and disability to many. Recently, glucosamine sulphate received attention as a putative agent that may retard cartilage degradation in Osteoarthritis. Moreover, studies show that glucosamine hydrochloride prevents lipoprotein protein oxidation and inhibits malondialdehyde adduct formation in chondrocyte cell matrix, suggesting that it inhibits advanced lipoxidation reactions. Together, the data suggest that the mechanism of decreasing collagen degradation in this in vitro model system by glucosamine may be mediated by the inhibition of advanced lipoxidation reaction, preventing the oxidation and loss of collagen matrix from labelled chondrocyte matrix.

Chondroitin sulphate has an effect on material properties and bone remodelling around hydroxyapatite / collagen composites.

Chondroitin Sulphate has an anti-inflammatory effect and increase the regeneration ability of injured bone.

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Ingredients:

Glucosamine Sulphate

Chondroitin sulphate

900mg / Each

200 Capsules per Bottle

Suggested use:

2 Capsules daily or directed by health professional